但这种垄断格局，即将被打破，多款在研新药正从作用机制到给药方式，向Vosoritide发起挑战。Ascendis的TransCon-CNP通过包裹技术延长了药物作用时间，实现了周剂给药，目前正处于FDA审批阶段；而BridgeBio的口服药Infigratinib，则从作用机制到用药体验实现全面突破。
Most userland implementations of custom ReadableStream instances do not typically bother with all the ceremony required to correctly implement both default and BYOB read support in a single stream – and for good reason. It's difficult to get right and most of the time consuming code is typically going to fallback on the default read path. The example below shows what a "correct" implementation would need to do. It's big, complex, and error prone, and not a level of complexity that the typical developer really wants to have to deal with:
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